Phytochemical, Antioxidant Profile and Targets Prediction Analysis of Tamarindus indica Bioactives

Abstract

Antioxidant potentials have been demonstrated to play important role in management and therapy against many disease conditions. Other associated role of this property was also found to be important in the field of nutrition and environmental ecotoxicology. Biological and environmental relevance has been reported on one of the most commonly abundant and under-utilized plant materials such as tamarind. The purpose of this work is to explore the phytochemical and antioxidant profile of tamarind leaves and pulp extract, as well as predicts its potentials in the management of several diseases conditions. Both the aqueous and methanol extract demonstrated appreciable content of total phenolics, flavonoids, anthocyanidins, and flavonols. Methanol leaves extract shows greater antioxidant capacity when compared with aqueous leaves/pulp and methanol pulp extract. The compounds found to be present in the extracted have been reported to confer antioxidant potentials. Tamarindus indica extract demonstrated high content of antioxidant phytochemicals and antioxidant capacity which was fully backed by the individual compound contained. Antioxidant activity is higher in methanol extract than aqueous evidence by the phytochemical contents of the two extract. Targets prediction studies revealed the potential role of the bioactive in this plants against cellular proteins known to be implicated in diseases conditions. Therefore, since all this properties are directly or indirectly related to its rich antioxidant content, hence this property of tamarind extract could make it useful in the so many fields including medicinal chemistry, nutrition and environmental science.